HomeSportsBills vs. Lions odds, picks: 2021 NFL preseason Week 1 predictions, best...

Bills vs. Lions odds, picks: 2021 NFL preseason Week 1 predictions, best bets from expert on 40-22 run

The 2021 NFL season-opener is rapidly approaching, and the preseason is already underway. Last week, the Hall of Fame excited fans with an appetizer. This week, there is a full slate, including Friday’s tilt between the Buffalo Bills and Detroit Lions. Buffalo will travel 250 miles to Detroit for the first preseason game for each side.

Kickoff from Ford Field is set for 7 p.m. ET. The latest Bills vs. Lions odds from Caesars Sportsbook list Detroit as a 1.5-point home favorite. The over-under for total points expected is set at 36.5. Before locking in any Lions vs. Bills picks or NFL predictions, make sure you check out what SportsLine NFL expert R.J. White has to say.

CBS Sports’ Fantasy and gambling editor, White ended the 2020 season on an 80-59 run on all NFL picks, returning more than $1,400 during that span. It’s no surprise, as White has cashed huge twice in the world’s most prestigious football handicapping competition, the Las Vegas SuperContest. 

In addition, White has gone an astounding 40-22-2 on his last 64 NFL picks involving the Lions, returning more than $1,500. Anyone who has followed him is way up.

Now, White has set his sights on Bills vs. Lions and recently revealed his expert picks and analysis. You can head to SportsLine now to see his NFL picks. Now, here are several NFL odds and betting trends for Lions vs. Bills:

  • Bills vs. Lions spread: Lions -1.5
  • Bills vs. Lions over-under: 36.5 points 
  • Bills vs. Lions money line: Bills +100, Lions -120
  • BUF: Bills were 12-7 against the spread in 2020 
  • DET: Lions were 7-9 against the spread in 2020

Featured Game | Detroit Lions vs. Buffalo Bills

Why the Bills can cover

The Bills are clearly the more talented team from an overall roster standpoint. Yes, they are on the road, but that isn’t a massive roadblock in a preseason setting. Josh Allen won’t start, but Buffalo could also benefit from having a backup quarterback with starting experience in Mitchell Trubisky.

The Lions may push harder but, for as long as the Bills are using their better players, they have the advantage. There is also a chance that Detroit’s roster, even if deployed optimally, may not have enough to unseat Buffalo’s second unit over a small sample. The Lions have a weakness on the outside with a lack of explosion in their receiving corps, and that could benefit the Bills. 

Why the Lions can cover

Simply put, the Lions have a lot more to play for than the Bills. Granted, this is a preseason scenario with low stakes, but Dan Campbell’s regime has been predicated on a blue collar mentality. As such, it is reasonable to assume that the Lions will be invested in this game.

Furthermore, Detroit has more active evaluation to do with their core pieces, as Buffalo knows what they are and should be conservative in nature. Jared Goff projects to get reps for the Lions, and Detroit also stocked up on the offensive line, giving them hope of keeping their new quarterback clean. The Bills haven’t been dynamic in rushing the passer lately, ranking near the bottom of the NFL in sacks last season, and Buffalo’s second and third unit should see plenty of time on both sides of the ball.

How to make Bills vs. Lions picks

White has analyzed this matchup from all angles and while we can tell you he’s leaning over the total, he has discovered a critical X-factor that has him jumping all over one side of the spread. He’s only sharing that pick and the rest of his expert NFL analysis at SportsLine.

So who wins Bills vs. Lions? And which critical X-factor makes one side of the spread a massive value? Visit SportsLine now to see R.J. White’s Bills vs. Lions pick, all from the NFL expert who’s 40-22-2 on picks involving Detroit, and find out.

Must Read
Related News