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Northwestern vs. Ohio odds, line: 2021 college football picks, Week 4 predictions from proven computer model

The Northwestern Wildcats will take on the Ohio Bobcats at noon ET on Saturday at Ryan Field. The Wildcats are 1-2 overall and 1-1 at home. Northwestern is coming off a 30-23 loss to Duke. Ohio is 0-3 overall and 0-1 on the road. The Bobcats have lost three consecutive games to start the season for the first time since 2008. This will be the first meeting between Northwestern and Ohio in 13 years. 

Northwestern is favored by 14.5 points in the latest Northwestern vs. Ohio odds from Caesars Sportsbook, and the over-under is set at 48. Before locking in any Ohio vs. Northwestern picks, you to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. It also enters Week 4 of the 2021 season on a 72-58 run on all top-rated college football picks. Anyone who has followed it has seen huge returns..

Now, the model has set its sights on Northwestern vs. Ohio and just lock in its CFB picks and predictions. You can head to SportsLine now to see its picks. Here are several college football odds and betting lines for Northwestern vs. Ohio:

  • Northwestern vs. Ohio spread: Northwestern -14.5
  • Northwestern vs. Ohio over-under: 48 points
  • Northwestern vs. Ohio moneyline: Northwestern -700, Ohio +475

Featured Game | Northwestern Wildcats vs. Ohio Bobcats

What you need to know about Northwestern

Andrew Marty passed for two touchdowns and 151 yards on 16 attempts, in addition to rushing for one touchdown and 52 yards in the Wildcats’ loss to Duke last Saturday.  Marty was injured (upper body) in the fourth quarter. It is uncertain if he will get the start vs. Ohio, as Hunter Johnson and Ryan Hilinski are other options. Johnson had three interceptions and lost a fumble last week. 

Evan Hull has rushed for 262 yards and two touchdowns on 41 attempts. Northwestern has surrendered 30-plus points twice so far this season. 

What you need to know about Ohio

Ohio was on the wrong end of a 49-14 drubbing against Louisiana-Lafayette last Thursday. The Bobcats allowed Montrell Johnson to rush for four touchdowns and have now allowed nine rushing scores so far this season. Cameron Odom was held to six receiving yards on two receptions. 

 O’Shaan Allison totaled 92 yards from scrimmage and caught a touchdown pass in the loss. Kurtis Rourke completed 12-of-22 attempts for 122 yards and two touchdowns. This will be Ohio’s first game against a Big Ten team in four years. 

How to make Northwestern vs. Ohio picks

The model has simulated Northwestern vs. Ohio 10,000 times and the results are in. We can tell you that the model is leaning over on the point total, and it’s also generated a point-spread pick that is hitting in over 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Northwestern vs. Ohio? And which side of the spread hits more than 60 percent of the time? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks, and find out.

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